HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Isabel Iriepa Selected Research

Cholinesterases (Cholinesterase)

5/2020Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
12/2019New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition.
4/2019Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
8/2018Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile.
7/2018Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease.
10/2017Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.
3/2014Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease.
1/2014Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
6/2012Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Isabel Iriepa Research Topics

Disease

30Alzheimer Disease (Alzheimer's Disease)
08/2021 - 09/2011
3COVID-19
10/2021 - 11/2020
3Neuroblastoma
01/2020 - 07/2010
2Stroke (Strokes)
08/2021 - 01/2020
2Ischemia
08/2021 - 01/2020
1Ischemic Stroke
08/2021
1Virus Diseases (Viral Diseases)
11/2020
1Severe Acute Respiratory Syndrome
11/2020
1Infarction (Infarctions)
01/2020
1Cognitive Dysfunction
12/2019
1Neuroinflammatory Diseases
04/2019
1Amyloid Plaque
01/2019
1Disease Progression
07/2018
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2017

Drug/Important Bio-Agent (IBA)

11Biological ProductsIBA
08/2021 - 09/2011
9Cholinesterases (Cholinesterase)IBA
05/2020 - 06/2012
7Tacrine (Cognex)FDA Link
01/2021 - 12/2011
7Monoamine Oxidase (MAO)IBA
05/2020 - 09/2011
6LigandsIBA
11/2020 - 11/2011
6AntioxidantsIBA
10/2020 - 03/2016
5Cholinesterase Inhibitors (Anticholinesterases)IBA
04/2019 - 09/2011
4RotenoneIBA
08/2021 - 07/2010
4oligomycin AIBA
08/2021 - 07/2010
4Donepezil (Aricept)FDA LinkGeneric
08/2018 - 01/2014
3Neuroprotective AgentsIBA
08/2021 - 01/2015
3Pharmaceutical PreparationsIBA
11/2020 - 09/2011
3Calcium Channels (Calcium Channel)IBA
12/2019 - 07/2018
3Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
06/2014 - 01/2014
3AminesIBA
03/2014 - 06/2012
2Antiviral Agents (Antivirals)IBA
10/2021 - 11/2020
2Okadaic AcidIBA
08/2021 - 04/2019
2Glucose (Dextrose)FDA LinkGeneric
08/2021 - 01/2020
2Peptides (Polypeptides)IBA
08/2021 - 07/2020
2Oxygen (Dioxygen)IBA
08/2021 - 01/2020
2Amyloid beta-PeptidesIBA
07/2020 - 08/2016
2AcetylcholinesteraseIBA
05/2020 - 01/2015
2Cholinergic Agents (Cholinergics)IBA
04/2019 - 01/2019
2EnzymesIBA
03/2014 - 06/2012
1Ivermectin (Mectizan)FDA Link
10/2021
1Viral ProteinsIBA
10/2021
1Amyloid (Amyloid Fibrils)IBA
08/2021
1calcipotriene (calcipotriol)FDA LinkGeneric
08/2021
1Angiotensin-Converting Enzyme 2IBA
11/2020
1Proteins (Proteins, Gene)FDA Link
11/2020
1Dihydrotachysterol (AT 10)IBA
10/2020
11,4-dihydropyridine (dihydropyridine)IBA
10/2020
1Choline O-Acetyltransferase (Choline Acetyltransferase)IBA
07/2020
1QuinolonesIBA
05/2020
1Hydroxyl RadicalIBA
01/2020
1nitronesIBA
01/2020
1phenyl-N-tert-butylnitroneIBA
01/2020
1Superoxides (Superoxide)IBA
01/2020
1Histamine H3 Receptors (Histamine H3 Receptor)IBA
12/2019
1LipopolysaccharidesIBA
12/2019
16- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA
10/2019
1benzofuranIBA
09/2019
1Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA
04/2019
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2019
1Chalcone (Benzalacetophenone)IBA
07/2018
1KetonesIBA
07/2018
1Histamine (Histamine Dihydrochloride)FDA Link
10/2017
1quinolineIBA
08/2016
1Oxyquinoline (8 Hydroxyquinoline)FDA Link
06/2014
1Chelating AgentsIBA
06/2014
1propargylamineIBA
06/2014
1MetalsIBA
06/2014
1N- ((5- (3- (1- benzylpiperidin- 4- yl)propoxy)- 1- methyl- 1H- indol- 2- yl)methyl)- N- methylprop- 2- yn- 1- amineIBA
03/2014
1AmidesIBA
03/2014
1Carboxylic AcidsIBA
03/2014
1Oxidoreductases (Dehydrogenase)IBA
06/2012

Therapy/Procedure

18Therapeutics
08/2021 - 09/2011